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Targeted Allele Detail
Symbol: Gt(ROSA)26Sortm1.1(EYFP)Cos
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1.1, Frank Costantini
MGI ID: MGI:2449041
Synonyms: deltaNeo-YFP, R26R-YFP cre, ROSA-YFP
Gene: Gt(ROSA)26Sor  Location: Chr6:113044389-113054205 bp, - strand  Genetic Position: Chr6, 52.73 cM
Germline Transmission:  Earliest citation of germline transmission: J:80963
Parent Cell Line:  JM-1 (ES Cell)
Strain of Origin:  129X1/SvJ
Allele Type:    Targeted (Reporter)
Mutation:    Insertion
Mutation detailsThe floxed PGK-neo cassette was deleted by mating Gt(ROSA)26Sortm1(EYFP)Cos animals to the Tg(ACTB-cre)2Mrt line. Removal of the tpA stop sequence within the floxed neo cassette allows transcription of the EYFP reporter gene. (J:80963, J:98830)
Generation of Gt(ROSA)26Sortm1(EYFP)Cos or Gt(ROSA)26Sortm2(ECFP)Cos.
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gt(ROSA)26Sor Mutation:  758 strains or lines available
Original:  J:80963 Srinivas S, et al., Cre reporter strains produced by targeted insertion of EYFP and ECFP into the ROSA26 locus. BMC Dev Biol. 2001;1(1):4
All:  25 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.19
The Jackson Laboratory