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Gt(ROSA)26Sortm2(ECFP)Cos
Targeted Allele Detail
Nomenclature
Symbol: Gt(ROSA)26Sortm2(ECFP)Cos
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 2, Frank Costantini
MGI ID: MGI:2449039
Synonyms: R26RCFP, R26R-ECFP, ROSA-stopflox-CFP
Gene: Gt(ROSA)26Sor  Location: Chr6:113044389-113054205 bp, - strand  Genetic Position: Chr6, 52.73 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:80963
Parent Cell Line:  JM-1 (ES Cell)
Strain of Origin:  129X1/SvJ
Mutation
description
Allele Type:    Targeted (Conditional ready, Reporter)
Mutation:    Insertion
 
Mutation detailsA construct containing a floxed PGK-neo cassette and an enhanced cyan fluorescent protein (ECFP) gene was inserted into the Gt(ROSA)26Sor locus via homologous recombination. The floxed neo cassette contains a strong tpA stop sequence which prevents the transcription of ECFP. (J:80963)
Generation of Gt(ROSA)26Sortm1(EYFP)Cos or Gt(ROSA)26Sortm2(ECFP)Cos.
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 3 strains available      Cell Lines: 0 lines available
Carrying any Gt(ROSA)26Sor Mutation:  761 strains or lines available
References
Original:  J:80963 Srinivas S, et al., Cre reporter strains produced by targeted insertion of EYFP and ECFP into the ROSA26 locus. BMC Dev Biol. 2001;1(1):4
All:  16 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
05/17/2022
MGI 6.19
The Jackson Laboratory