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Targeted Allele Detail
Symbol: Gt(ROSA)26Sortm1(EYFP)Cos
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Frank Costantini
MGI ID: MGI:2449038
Synonyms: Gt(ROSA)26Sor-StopFlox-EYFP, LSLYFP, R26eYFP, R26::EYFP, R26ReYFP, R26ReYFP, R26R EYFP, R26R-EYFP, R26RYFP, R26RYFP, R26-stop-EYFP, R26Y, r26YFP, R26-YFP, R26YY, R-EYFP, ROSA26-EYFP, Rosa26-eYFPtg, ROSA26floxSTOPfloxYFP, ROSA26floxSTOP-YFP, ROSA26-LoxP-STOP-LoxP-EYFP, ROSA26-loxP-Stop-loxP-YF, ROSA26-lsl-EYFP, Rosa26LSL-YFP, Rosa26R(YFP), ROSA26R-YFP, Rosa26stopfloxYFP, Rosa26-Stopfl-YFP, ROSA26-stop-YFP reporter, Rosa26YFP, ROSA26-YFP, Rosa26-YFPfl, Rosa26-YFPst, Rosa26YFPStop, ROSAEYFP, ROSA-LSL-YFP, ROSA-YFP, Rosa-YFPf, RYR, YFP
Gene: Gt(ROSA)26Sor  Location: Chr6:113044389-113054205 bp, - strand  Genetic Position: Chr6, 52.73 cM
Germline Transmission:  Earliest citation of germline transmission: J:80963
Parent Cell Line:  JM-1 (ES Cell)
Strain of Origin:  129X1/SvJ
Allele Type:    Targeted (Conditional ready, Reporter)
Mutation:    Insertion
Mutation detailsA construct containing a floxed PGK-neo cassette and an enhanced yellow fluorescent protein (EYFP) gene was inserted into the Gt(ROSA)26Sor locus via homologous recombination. The floxed neo cassette contains a strong tpA stop sequence which prevents the transcription of EYFP. (J:80963)
Generation of Gt(ROSA)26Sortm1(EYFP)Cos or Gt(ROSA)26Sortm2(ECFP)Cos.
View phenotypes and curated references for all genotypes (concatenated display).
In Mice Carrying this Mutation: 431 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 9 strains available      Cell Lines: 0 lines available
Carrying any Gt(ROSA)26Sor Mutation:  745 strains or lines available
Original:  J:80963 Srinivas S, et al., Cre reporter strains produced by targeted insertion of EYFP and ECFP into the ROSA26 locus. BMC Dev Biol. 2001;1(1):4
All:  1886 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.17
The Jackson Laboratory