Tg(tetO-Utrn)1Ked
Transgene Detail
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| Symbol: |
Tg(tetO-Utrn)1Ked |
| Name: |
transgene insertion 1, Kay E Davies |
| MGI ID: |
MGI:2448084 |
| Synonyms: |
Tg(UTR-TET)Ked, Utr-TET |
| Transgene: |
Tg(tetO-Utrn)1Ked Location: unknown
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| Alliance: |
Tg(tetO-Utrn)1Ked page
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| Strain of Origin: |
Not Specified
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| Transgene Type: |
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Transgenic (Inducible, Inserted expressed sequence) |
| Inducer: |
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doxycycline/tetracycline |
| Mutation: |
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Insertion
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Mutation details: A full-length cDNA encoding mouse utrophin with an N-terminal FLAG epitope tag was inserted between the cytomegalovirus (CMV) minimal promoter and polyadenylation signal, all downstream of the tetracycline operator (tetracycline responsive element). Tissue-specific tetracycline transactivator (tTA) or reverse transactivator (rtTA) expression from a second transgene permits regulation of utrophin expression by administration of doxycycline in drinking water.
(J:80809)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 2 strains available
Cell Lines: 0 lines available
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| Original: |
J:80809 Squire S, et al., Prevention of pathology in mdx mice by expression of utrophin: analysis using an inducible transgenic expression system. Hum Mol Genet. 2002 Dec 15;11(26):3333-44 |
| All: |
1 reference(s) |
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Analysis Tools
