Rpl38^Rbt
Chemically induced Allele Detail

Summary

• Symbol: Rpl38^Rbt
• Name: ribosomal protein L38; Rabo torcido
• MGI ID: MGI:2447994
• Gene: Rpl38 Location: Chr11:114559350-114563157 bp, + strand Genetic Position: Chr11, 79.82 cM, cytoband G1
• Alliance: Rpl38^Rbt page

Skeletal analysis of Rbt/+ and wild-type newborn mice.

Show the 2 phenotype image(s) involving this allele.

Mutation origin

• Strain of Origin: mixed

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Insertion
• Mutation details: An ENU-induced mutation that was generated at the Pasteur Institute in 1996. The molecular lesion is an insertion of the dinucleotide AG preceding the first codon in exon 3. This insertion results in a change of the acceptor splice site, leading to a frameshift mutation resulting in a premature stop codon. (J:173414)
• Inheritance: Semidominant

Expression

In Structures Affected by this Mutation:

9 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rpl38 Mutation: 18 strains or lines available

References

• Original: J:37422 Hustert E, et al., Rbt (Rabo torcido), a new mouse skeletal mutation involved in anteroposterior patterning of the axial skeleton, maps close to the Ts (tail-short) locus and distal to the Sox9 locus on chromosome 11. Mamm Genome. 1996 Dec;7(12):881-5
• All: 2 reference(s)