About   Help   FAQ
The MGI survey is now closed.
Thanks for your support!
Targeted Allele Detail
Symbol: Dlx5/Dlx6tm1Levi
Name: distal-less homeobox 6; targeted mutation 1, Giovanni Levi
MGI ID: MGI:2447625
Synonyms: Dlx5/6-, Dlx5-Dlx6-
Gene: Dlx6  Location: Chr6:6863334-6868568 bp, + strand  Genetic Position: Chr6, 2.83 cM
Germline Transmission:  Earliest citation of germline transmission: J:77244
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intergenic deletion
Mutation detailsDlx5 and Dlx6 were deleted and replaced with lacZ-floxed-RSV-neo construct via a single homologous recombination event. The gene targeting event generated a transcriptionally silent genomic duplication spanning Dlx5 and part of Dxl6. Absence of gene expression was confirmed by RT-PCR and whole mount in situ hybridization. (J:77244)
View phenotypes for all genotypes (concatenated display).
Disease models
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Dlx6 Mutation:  4 strains or lines available
Original:  J:77244 Merlo GR, et al., Mouse model of split hand/foot malformation type I. Genesis. 2002 Jun;33(2):97-101
All:  15 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
MGI 5.21
The Jackson Laboratory