Tg(MMTV-Myc)164-4Led
Transgene Detail

Summary

• Symbol: Tg(MMTV-Myc)164-4Led
• Name: transgene insertion 164-4, Philip Leder
• MGI ID: MGI:2447518
• Synonyms: 164-4
• Transgene: Tg(MMTV-Myc)164-4Led Location: unknown
• Alliance: Tg(MMTV-Myc)164-4Led page

Transgene origin

• Strain of Origin: (CD-1 x C57BL/6J)F1

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(MMTV-Myc)164-4Led expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Myc (MGI:97250)

• Mutation details: This transgene contains the mouse mammary tumor virus promoter and a portion of the mouse Myc (myelocytomatosis) oncogene minus exon 1. The construct was also called MTV-Xba myc. The founder mouse carried 2 insertions of the transgene that were later separated via breeding into lines carrying either Tg(MMTV-cmyc)164-4aLed or Tg(MMTV-cmyc)164-4bLed. (J:29013)

Tumor Data

List all tumor models in MMHCdb carrying Tg(MMTV-Myc)164-4Led

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

Notes

Lines 165-1a and 165-1b also carry the MTV-Xba myc construct. The construct was also called "MTV-Xba myc" or "MMTV/c-myc" or "MTV-Xba" or "MMTV-Xba myc".

References

• Original: J:29013 Stewart TA, et al., Spontaneous mammary adenocarcinomas in transgenic mice that carry and express MTV/myc fusion genes. Cell. 1984 Oct;38(3):627-37
• All: 1 reference(s)