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Tg(MMTV-Myc)141-3Led
Transgene Detail
Nomenclature
Symbol: Tg(MMTV-Myc)141-3Led
Name: transgene insertion 141-3, Philip Leder
MGI ID: MGI:2447500
Synonyms: 141-3, M strain, MTV-H3 141-3, TG.M
Transgene: Tg(MMTV-Myc)141-3Led  Location: unknown  
Transgene
origin
Strain of Origin:  (CD-1 x C57BL/6J)F1
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(MMTV-Myc)141-3Led expresses 1 gene
 
Mutation detailsThis transgene contains the MMTV (mouse mammary tumor virus) promoter and the mouse Myc (myelocytomatosis) oncogene. The construct is also called "MTV-H3 myc." The transgene was expressed in salivary gland, intestine, and mammary gland. Expression of the transgene was not detected in thymus, pancreas, spleen, kidney, testis, liver, heart, lung, muscle, brain, or preputial gland. (J:29013)
Phenotypes
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Disease models
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Notes
Lines 139-1, 143-3, and 143-5 also carry this construct. The construct is also called "MMTV/c-myc'" "MTV-H3" "MTV-H3 myc" or "MMTV-H3 myc" or "TG.M."

References
Original:  J:29013 Stewart TA, et al., Spontaneous mammary adenocarcinomas in transgenic mice that carry and express MTV/myc fusion genes. Cell. 1984 Oct;38(3):627-37
All:  29 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
01/20/2015
MGI 5.21
The Jackson Laboratory