Snai2tm1Look
Targeted Allele Detail
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Symbol: |
Snai2tm1Look |
Name: |
snail family zinc finger 2; targeted mutation 1, A Thomas Look |
MGI ID: |
MGI:2447174 |
Synonyms: |
Slug-/- |
Gene: |
Snai2 Location: Chr16:14523716-14527249 bp, + strand Genetic Position: Chr16, 10.07 cM
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Alliance: |
Snai2tm1Look page
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Germline Transmission: |
Earliest citation of germline transmission:
J:80652
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Parent Cell Line: |
RW-4 (ES Cell)
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Strain of Origin: |
129X1/SvJ
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Allele Type: |
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Targeted (Null/knockout) |
Mutations: |
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Insertion, Intragenic deletion
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Mutation details: A 1.2 kb region of the gene encompassing exon 1 and part of exon 2 was replaced with a neomycin resistance cassette via homologous recombination. Northern blot analysis of mouse embryonic fibroblasts derived from homozygous mutant embryos confirmed the absence of gene expression.
(J:80652)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Snai2 Mutation: |
34 strains or lines available
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Original: |
J:80652 Inoue A, et al., Slug, a highly conserved zinc finger transcriptional repressor, protects hematopoietic progenitor cells from radiation-induced apoptosis in vivo. Cancer Cell. 2002 Oct;2(4):279-88 |
All: |
3 reference(s) |
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