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Tg(Gata1-cre)1Sho
Transgene Detail
Nomenclature
Symbol: Tg(Gata1-cre)1Sho
Name: transgene insertion 1, Stuart Orkin
MGI ID: MGI:2446599
Synonyms: GATA1-Cre
Transgene: Tg(Gata1-cre)1Sho  Location: unknown  
Transgene
origin
Strain of Origin:  CD-1
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Mutation detailsSequence encoding cre recombinase was adjoined to the murine Gata1 promoter region. The expanded expression pattern (relative to the endogenous Gata1 gene) has been attributed to leaky cre expression during an early stage of embryogenesis. While the Gata1 promoter was putatively a hematopoietic-specific promoter, efficient cre mediated excision has been observed in germ cells. (J:64291)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Gata1     Summary of all recombinase alleles driven by Gata1. Comparative matrix view of recombinase activities
 

Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:64291 Mao X, et al., Improved reporter strain for monitoring Cre recombinase-mediated DNA excisions in mice. Proc Natl Acad Sci U S A. 1999 Apr 27;96(9):5037-42
All:  24 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
12/03/2019
MGI 6.14
The Jackson Laboratory