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Cpb2tm1Efp
Targeted Allele Detail
Nomenclature
Symbol: Cpb2tm1Efp
Name: carboxypeptidase B2 (plasma); targeted mutation 1, Edward F Plow
MGI ID: MGI:2445419
Synonyms: pCPB-
Gene: Cpb2  Location: Chr14:75242287-75283551 bp, + strand  Genetic Position: Chr14, 39.73 cM, cytoband D2
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:80114
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
 
Mutation detailsExon 2 was disrupted by the insertion of a neomycin selection cassette. No transcript was detected by Northern blot analysis of homozygous mutant liver. (J:80114)
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cpb2 Mutation:  9 strains or lines available
References
Original:  J:80114 Swaisgood CM, et al., In vivo regulation of plasminogen function by plasma carboxypeptidase B. J Clin Invest. 2002 Nov;110(9):1275-82
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/20/2016
MGI 6.05
The Jackson Laboratory