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Targeted Allele Detail
Symbol: Ugcgtm3Rlp
Name: UDP-glucose ceramide glucosyltransferase; targeted mutation 3, Richard L Proia
MGI ID: MGI:2445417
Synonyms: UgcgLacz
Gene: Ugcg  Location: Chr4:59189507-59222833 bp, + strand  Genetic Position: Chr4, 32.44 cM, cytoband B3
Germline Transmission:  Earliest citation of germline transmission: J:80111
Parent Cell Line:  TC1/TC-1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Insertion
Mutation detailsA promoter-less IRES-lacZ-neo cassette was inserted into exon 8 via homologous recombination. Southern blot analysis was used to identify and confirm the correct gene targeting event in embryonic stem cells. (J:80111)
View phenotypes and curated references for all genotypes (concatenated display).
In Mice Carrying this Mutation: 9 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ugcg Mutation:  3 strains or lines available
Original:  J:80111 Yamashita T, et al., Early developmental expression of the gene encoding glucosylceramide synthase, the enzyme controlling the first committed step of glycosphingolipid synthesis. Biochim Biophys Acta. 2002 Dec 19;1573(3):236-40
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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MGI 6.15
The Jackson Laboratory