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Tg(RIP1-Tag)2Dh
Transgene Detail
Nomenclature
Symbol: Tg(RIP1-Tag)2Dh
Name: transgene insertion 2, Douglas Hanahan
MGI ID: MGI:2429941
Synonyms: Rip1Tag2, RIP1-Tag2, RIP-Tag2, RT2
Transgene: Tg(RIP1-Tag)2Dh  Location: unknown  Genetic Position: Chr2, Syntenic
Transgene
origin
Strain of Origin:  (C57BL/6J x DBA/2J)F2
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Mutation details695 bp of 5' flanking DNA from the rat insulin promoter was used to drive expression of large T antigen in pancreatic beta cells. (J:50695)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 3 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 3 strains available      Cell Lines: 0 lines available
Notes
Four transgenic lines were produced. Transgenic mice die prematurely at 9-12 weeks of age.
References
Original:  J:50695 Hanahan D, Heritable formation of pancreatic beta-cell tumours in transgenic mice expressing recombinant insulin/simian virus 40 oncogenes. Nature. 1985 May 9-15;315(6015):115-22
All:  148 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
05/14/2019
MGI 6.14
The Jackson Laboratory