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Ryr3tm2Tno
Targeted Allele Detail
Nomenclature
Symbol: Ryr3tm2Tno
Name: ryanodine receptor 3; targeted mutation 2, Tetsuo Noda
MGI ID: MGI:2429753
Gene: Ryr3  Location: Chr2:112631355-113217096 bp, - strand  Genetic Position: Chr2, 57.2 cM, cytoband E5-F3
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:34908
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Disruption caused by insertion of vector
 
Mutation detailsExon 2 was replaced with a neomycin selection cassette inserted by homologous recombination. No protein was detected by Western blot analysis of brain tissue obtained from homozygous mutant mice. (J:34908)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ryr3 Mutation:  116 strains or lines available
References
Original:  J:34908 Takeshima H, et al., Generation and characterization of mutant mice lacking ryanodine receptor type 3. J Biol Chem. 1996 Aug 16;271(33):19649-52
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
03/21/2017
MGI 6.08
The Jackson Laboratory