Cd200tm1Jods
Targeted Allele Detail
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Symbol: |
Cd200tm1Jods |
Name: |
CD200 antigen; targeted mutation 1, Jonathon D Sedgwick |
MGI ID: |
MGI:2429651 |
Synonyms: |
CD200- |
Gene: |
Cd200 Location: Chr16:45382135-45409053 bp, - strand Genetic Position: Chr16, 29.53 cM, cytoband A1
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Germline Transmission: |
Earliest citation of germline transmission:
J:65982
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
C57BL/6 |
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Allele Type: |
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Targeted (Null/knockout) |
Mutations: |
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Insertion, Intragenic deletion
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Mutation details: A portion of exon 3 was replaced by a neomycin selection cassette. Protein expression was examined by immunohistochemical and flow cytometric analyses and determined to be absent in the CNS, B cells, follicular dendritic cells, and splenic endothelium of homozygous mutant mice.
(J:65982)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Cd200 Mutation: |
12 strains or lines available
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Original: |
J:65982 Hoek RM, et al., Down-regulation of the macrophage lineage through interaction with OX2 (CD200). Science. 2000 Dec 1;290(5497):1768-71 |
All: |
18 reference(s) |
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