Etia^C57BL/6J
QTL Variant Detail

Summary

• QTL variant: Etia^C57BL/6J
• Name: ethanol induced activation; C57BL/6J
• MGI ID: MGI:2429577
• QTL: Etia Location: Chr16:80313907-80314016 bp Genetic Position: Chr16, cM position of peak correlated region/allele: 45.89 cM
• QTL Note: genome coordinates based on the marker associated with the peak LOD score

Variant origin

• Strain of Specimen: C57BL/6J

Variant description

• Allele Type: QTL

Notes

Mapping and Phenotype information for this QTL, its variants and associated markers

J:66629

23 AXB and BXA recombinant inbred (RI) strains were analyzed for QTLs affecting ethanol induced locomotor activation (A = A/J, B = C57BL/6J). Animals were monitored in an open field test following injection with 10% ethanol solution. Several suggestive loci mapped to mouse chromosomes 2, 4, 8, 12, 17, and 19. A significant QTL mapped to mouse Chromosome 16 at approximately 55 cM (LOD = 4.21 at D16Mit203) via composite interval mapping (CIM) where the effects of other QTLs (Es1 and Iapls3-7) were controlled.

References

• Original: J:66629 Gill K, et al., Alcohol-induced locomotor activation in C57BL/6J, A/J, and AXB/BXA recombinant inbred mice: strain distribution patterns and quantitative trait loci analysis. Psychopharmacology (Berl). 2000 Jul;150(4):412-21
• All: 1 reference(s)