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Tyk2tm1Shmd
Targeted Allele Detail
Nomenclature
Symbol: Tyk2tm1Shmd
Name: tyrosine kinase 2; targeted mutation 1, Kazuya Shimoda
MGI ID: MGI:2389582
Synonyms: Tyk2-
Gene: Tyk2  Location: Chr9:21104069-21127346 bp, - strand  Genetic Position: Chr9, 7.71 cM, cytoband A3
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:65409
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tyk2 Mutation:  9 strains or lines available
References
Original:  J:65409 Shimoda K, et al., Tyk2 plays a restricted role in IFN alpha signaling, although it is required for IL-12-mediated T cell function. Immunity. 2000 Oct;13(4):561-71
All:  19 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/18/2014
MGI 5.20
The Jackson Laboratory