About   Help   FAQ
Bace1tm1Pcw
Targeted Allele Detail
Nomenclature
Symbol: Bace1tm1Pcw
Name: beta-site APP cleaving enzyme 1; targeted mutation 1, Philip C Wong
MGI ID: MGI:2389228
Synonyms: Bace1-, BACE1-
Gene: Bace1  Location: Chr9:45838580-45864399 bp, + strand  Genetic Position: Chr9, 25.22 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:79847
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation details
Phenotypes
Loading...
View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Bace1 Mutation:  5 strains or lines available
References
Original:  J:79847 Cai H, et al., BACE1 is the major beta-secretase for generation of Abeta peptides by neurons. Nat Neurosci. 2001 Mar;4(3):233-4
All:  31 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
09/16/2014
MGI 5.19
The Jackson Laboratory