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Cdh1tm2.1Kem
Targeted Allele Detail
Nomenclature
Symbol: Cdh1tm2.1Kem
Name: cadherin 1; targeted mutation 2.1, Rolf Kemler
MGI ID: MGI:2389021
Synonyms: E-cadherinflox-del
Gene: Cdh1  Location: Chr8:106603351-106670246 bp, + strand  Genetic Position: Chr8, 53.18 cM, cytoband D
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:77170
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA region encompassing exons 6 through 10 was deleted from Cdh1tm2Kem via in vivo cre mediated recombination of flanking loxP sites. (J:77170)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cdh1 Mutation:  120 strains or lines available
References
Original:  J:77170 Boussadia O, et al., E-cadherin is a survival factor for the lactating mouse mammary gland. Mech Dev. 2002 Jul;115(1-2):53-62
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
06/30/2020
MGI 6.15
The Jackson Laboratory