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PhexHyp-Duk
Spontaneous Allele Detail
Summary
Symbol: PhexHyp-Duk
Name: phosphate regulating endopeptidase homolog, X-linked; hypophosphatemia, Duke
MGI ID: MGI:2388890
Gene: Phex  Location: ChrX:155945071-156198282 bp, - strand  Genetic Position: ChrX, 72.38 cM
Alliance: PhexHyp-Duk page
PhexHyp-Duk/Y with littermate +/Y control

Show the 4 phenotype image(s) involving this allele.

Mutation
origin
Strain of Origin:  CAnBomUrd.Cg-Foxn1nu
Mutation
description
Allele Type:    Spontaneous
Mutation:    Intragenic deletion
 
Mutation detailsGenomic PCR and Southern blot analysis indicated a deletion of at least 30 kb containing exons 13 and 14 of the Phex gene.
Inheritance:    Semidominant
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 27 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 3 strains available      Cell Lines: 0 lines available
Carrying any Phex Mutation:  21 strains or lines available
References
Original:  J:88352 Lorenz-Depiereux B, et al., New intragenic deletions in the Phex gene clarify X-linked hypophosphatemia-related abnormalities in mice. Mamm Genome. 2004 Mar;15(3):151-61
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/22/2022
MGI 6.22
The Jackson Laboratory