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Stat4tm1Jni
Targeted Allele Detail
Nomenclature
Symbol: Stat4tm1Jni
Name: signal transducer and activator of transcription 4; targeted mutation 1, James N Ihle
MGI ID: MGI:2388732
Synonyms: stat4-
Gene: Stat4  Location: Chr1:51987148-52107189 bp, + strand  Genetic Position: Chr1, 26.67 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:34060
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
 
Mutation detailsExon 3 was disrupted by the insertion of a hygromycin selection cassette. Protein was undetected by immunoprecipitation followed by Western blot analysis of spleen and testes extracts. (J:34060)
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Stat4 Mutation:  13 strains or lines available
References
Original:  J:34060 Thierfelder WE, et al., Requirement for Stat4 in interleukin-12-mediated responses of natural killer and T cells. Nature. 1996 Jul 11;382(6587):171-4
All:  18 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
02/25/2015
MGI 5.21
The Jackson Laboratory