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Mycntm1.1Psk
Targeted Allele Detail
Nomenclature
Symbol: Mycntm1.1Psk
Name: v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived; targeted mutation 1.1, Paul S Knoepfler
MGI ID: MGI:2388718
Synonyms: Mycntm1.1Rne, N-mycdelta
Gene: Mycn  Location: Chr12:12936096-12941914 bp, - strand  Genetic Position: Chr12, 6.14 cM, cytoband A3-B
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:79489
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsTransient expression of cre recombinase in ES cells excised the floxed fragment containing exons 2 and 3 and a neo cassette from Nmyc1tm1Psk. (J:79489)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Mycn Mutation:  17 strains or lines available
References
Original:  J:79489 Knoepfler PS, et al., N-myc is essential during neurogenesis for the rapid expansion of progenitor cell populations and the inhibition of neuronal differentiation. Genes Dev. 2002 Oct 15;16(20):2699-712
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
10/10/2017
MGI 6.10
The Jackson Laboratory