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Targeted Allele Detail
Symbol: Cnga3tm1Biel
Name: cyclic nucleotide gated channel alpha 3; targeted mutation 1, Martin Biel
MGI ID: MGI:2388388
Synonyms: CNG3-
Gene: Cnga3  Location: Chr1:37214434-37263384 bp, + strand  Genetic Position: Chr1, 15.46 cM, cytoband B
Retinal morphology of 2 month old Cnga3tm1Biel/Cnga3tm1Biel and wild-type mice

Show the 1 phenotype image(s) involving this allele.

Germline Transmission:  Earliest citation of germline transmission: J:56020
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsThe gene was disrupted by replacement of exon 7 with a neomycin resistance cassette. Absence of gene expression in homozygous mutant animals was confirmed by RT-PCR analysis of retina RNA. (J:56020)
View phenotypes for all genotypes (concatenated display).
Disease models
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cnga3 Mutation:  2 strains or lines available
Original:  J:56020 Biel M, et al., Selective loss of cone function in mice lacking the cyclic nucleotide-gated channel CNG3. Proc Natl Acad Sci U S A. 1999 Jun 22;96(13):7553-7
All:  28 reference(s)

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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