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Targeted Allele Detail
Symbol: Il4tm1Wep
Name: interleukin 4; targeted mutation 1, William E Paul
MGI ID: MGI:2388163
Gene: Il4  Location: Chr11:53612460-53618665 bp, - strand  Genetic Position: Chr11, 31.97 cM
Germline Transmission:  Earliest citation of germline transmission: J:67964
Parent Cell Line:  E14.1 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Disruption caused by insertion of vector
Mutation detailsExon 1 and 178 nucleotides of intron 1 were replaced with an enhanced GFP floxed-neo construct via homologous recombination. Heterozygous mutant animals were identified by PCR genotype analysis. (J:67964)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Il4 Mutation:  29 strains or lines available
Original:  J:67964 Hu-Li J, et al., Regulation of expression of IL-4 alleles: analysis using a chimeric GFP/IL-4 gene. Immunity. 2001 Jan;14(1):1-11
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory