About   Help   FAQ
Rgs2tm1Pngr
Targeted Allele Detail
Nomenclature
Symbol: Rgs2tm1Pngr
Name: regulator of G-protein signaling 2; targeted mutation 1, Josef M Penninger
MGI ID: MGI:2388144
Synonyms: rgs2-
Gene: Rgs2  Location: Chr1:143999338-144004161 bp, - strand  Genetic Position: Chr1, 62.56 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:77273
Parent Cell Line:  E14K (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe gene was disrupted by replacement of exons 4 and 5 with a PGK-neo cassette in the reverse orientation. Northern blot analysis of brain RNA using a full-length cDNA probe confirmed the null allele in homozygous mutant animals. (J:77273)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rgs2 Mutation:  7 strains or lines available
References
Original:  J:77273 Oliveira-Dos-Santos AJ, et al., Regulation of T cell activation, anxiety, and male aggression by RGS2. Proc Natl Acad Sci U S A. 2000 Oct 24;97(22):12272-7
All:  25 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
05/16/2017
MGI 6.09
The Jackson Laboratory