About   Help   FAQ
Slc31a1tm1Djt
Targeted Allele Detail
Nomenclature
Symbol: Slc31a1tm1Djt
Name: solute carrier family 31, member 1; targeted mutation 1, Dennis J Thiele
MGI ID: MGI:2388121
Synonyms: Ctr1-/-
Gene: Slc31a1  Location: Chr4:62360727-62391769 bp, + strand  Genetic Position: Chr4, 33.11 cM, cytoband C1-C2
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:69897
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe entire coding region of the gene was deleted and replaced with a PGK-neo cassette via homologous recombination. Homozygous mutant embryos were observed at day E10.5, but not did not survive past day E12.5. (J:69897)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Slc31a1 Mutation:  35 strains or lines available
References
Original:  J:69897 Lee J, et al., Essential role for mammalian copper transporter Ctr1 in copper homeostasis and embryonic development. Proc Natl Acad Sci U S A. 2001 Jun 5;98(12):6842-7
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
05/16/2017
MGI 6.09
The Jackson Laboratory