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Targeted Allele Detail
Symbol: Slc31a1tm1Djt
Name: solute carrier family 31, member 1; targeted mutation 1, Dennis J Thiele
MGI ID: MGI:2388121
Synonyms: Ctr1-/-
Gene: Slc31a1  Location: Chr4:62360727-62391769 bp, + strand  Genetic Position: Chr4, 33.11 cM, cytoband C1-C2
Germline Transmission:  Earliest citation of germline transmission: J:69897
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsThe entire coding region of the gene was deleted and replaced with a PGK-neo cassette via homologous recombination. Homozygous mutant embryos were observed at day E10.5, but not did not survive past day E12.5. (J:69897)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Slc31a1 Mutation:  36 strains or lines available
Original:  J:69897 Lee J, et al., Essential role for mammalian copper transporter Ctr1 in copper homeostasis and embryonic development. Proc Natl Acad Sci U S A. 2001 Jun 5;98(12):6842-7
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.11
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