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Amphtm1Pdc
Targeted Allele Detail
Nomenclature
Symbol: Amphtm1Pdc
Name: amphiphysin; targeted mutation 1, Pietro De Camilli
MGI ID: MGI:2388118
Gene: Amph  Location: Chr13:18948351-19150915 bp, + strand  Genetic Position: Chr13, 6.89 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:75306
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129/Sv
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExon 1 was disrupted by the insertion of a neomycin selection cassette. Protein was undetected by Western blot analysis and immunofluorescence staining. (J:75306)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Amph Mutation:  38 strains or lines available
References
Original:  J:75306 Di Paolo G, et al., Decreased synaptic vesicle recycling efficiency and cognitive deficits in amphiphysin 1 knockout mice. Neuron. 2002 Feb 28;33(5):789-804
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
10/10/2017
MGI 6.10
The Jackson Laboratory