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Ltbtm1Avt
Targeted Allele Detail
Nomenclature
Symbol: Ltbtm1Avt
Name: lymphotoxin B; targeted mutation 1, Alexei V Tumanov
MGI ID: MGI:2388016
Synonyms: ltbflox
Gene: Ltb  Location: Chr17:35194507-35196305 bp, + strand  Genetic Position: Chr17, 18.59 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:79129
Parent Cell Line:  Bruce 4 (ES Cell)
Strain of Origin:  B6.Cg-Thy1a
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsThe endogenous allele was left flanked by loxP sites after a floxed neomycin selection cassette was excised via the transient expression of cre recombinase in vitro. (J:79129)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 4 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ltb Mutation:  10 strains or lines available
References
Original:  J:79129 Tumanov A, et al., Distinct role of surface lymphotoxin expressed by B cells in the organization of secondary lymphoid tissues. Immunity. 2002 Sep;17(3):239-50
All:  11 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/18/2020
MGI 6.14
The Jackson Laboratory