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Drd2tm1Ebo
Targeted Allele Detail
Nomenclature
Symbol: Drd2tm1Ebo
Name: dopamine receptor D2; targeted mutation 1, Emiliana Borrelli
MGI ID: MGI:2387895
Synonyms: D2R-
Gene: Drd2  Location: Chr9:49340662-49407214 bp, + strand  Genetic Position: Chr9, 26.72 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:29045
Parent Cell Line:  P1 (ES Cell)
Strain of Origin:  129S2/SvPas
Mutation
description
Allele Type:    Targeted (knock-out)
Mutations:    Insertion, Intragenic deletion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Drd2 Mutation:  16 strains or lines available
Notes

Phenotypic Similarity to Human Syndrome: Cushing's syndrome

Phenotypic Similarity to Human Syndrome: Parkinson Disease (J:29045)

References
Original:  J:29045 Baik JH, et al., Parkinsonian-like locomotor impairment in mice lacking dopamine D2 receptors. Nature. 1995 Oct 5;377(6548):424-8
All:  31 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory