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Brs3tm1Hoh
Targeted Allele Detail
Nomenclature
Symbol: Brs3tm1Hoh
Name: bombesin-like receptor 3; targeted mutation 1, Hiroko Ohki-Hamazaki
MGI ID: MGI:2387858
Synonyms: BRS-3-deficient
Gene: Brs3  Location: ChrX:57043074-57048758 bp, + strand  Genetic Position: ChrX, 30.78 cM, cytoband A7.1-A7.2
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:44242
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExon 2 was replaced by with a neomycin selection cassette inserted via homologous recombination. Transcript was undetected in hemizygous mutant mice via RT-PCR analysis. (J:44242)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Brs3 Mutation:  8 strains or lines available
References
Original:  J:44242 Ohki-Hamazaki H, et al., Mice lacking bombesin receptor subtype-3 develop metabolic defects and obesity. Nature. 1997 Nov 13;390(6656):165-9
All:  7 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/28/2017
MGI 6.11
The Jackson Laboratory