Tg(PBEcoRI)22Jsn
Transgene Detail

Summary

• Symbol: Tg(PBEcoRI)22Jsn
• Name: transgene insertion 22, James S Norris
• MGI ID: MGI:2387686
• Synonyms: PBEcoRI, Tg(Pbsn-EcoRI)22LJsn
• Transgene: Tg(PBEcoRI)22Jsn Location: unknown
• Alliance: Tg(PBEcoRI)22Jsn page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: A cDNA encoding the EcoRI restriction enzyme driven in the prostate by the rat probasin gene promoter (-426 to +28). Expression of the transgene was verified by Western blot analysis. A single copy of the transgene was present in this founder line. (J:63563)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

Notes

Two lines were produced: 22L and 25N (see also Tg(PbEcoRI)25Jsn). Each carries one copy of the transgene.

References

• Original: J:63563 Voelkel-Johnson C, et al., Genomic instability-based transgenic models of prostate cancer. Carcinogenesis. 2000 Aug;21(8):1623-7
• All: 1 reference(s)