Vcam1^tm2.1Roml
Targeted Allele Detail

Summary

• Symbol: Vcam1^tm2.1Roml
• Name: vascular cell adhesion molecule 1; targeted mutation 2.1, Mark A Labow
• MGI ID: MGI:2387554
• Synonyms: VCAM^del
• Gene: Vcam1 Location: Chr3:115903669-115923337 bp, - strand Genetic Position: Chr3, 50.17 cM
• Alliance: Vcam1^tm2.1Roml page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:43561
• Parent Cell Line: W9.5/W95 (ES Cell)
• Strain of Origin: 129S1/Sv-Oca2⁺ Tyr⁺ Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: The proximal promoter, exons 1 and 2, and the inserted neo gene were deleted from Vcam1^tm2Roml via in vivo cre mediated recombination. (J:43561)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Vcam1 Mutation: 42 strains or lines available

References

• Original: J:43561 Terry RW, et al., Cre-mediated generation of a VCAM-1 null allele in transgenic mice. Transgenic Res. 1997 Sep;6(5):349-56
• All: 1 reference(s)