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Targeted Allele Detail
Symbol: Htr1atm2Rhn
Name: 5-hydroxytryptamine (serotonin) receptor 1A; targeted mutation 2, Rene Hen
MGI ID: MGI:2387416
Synonyms: Htr1aKO, Htr1atetO
Gene: Htr1a  Location: Chr13:105443693-105448133 bp, + strand  Genetic Position: Chr13, 56.92 cM
Germline Transmission:  Earliest citation of germline transmission: J:75722
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
Mutation detailsTranscription of the coding region was blocked by the insertion of a neomycin resistance gene and tetO binding sites in the 5' untranslated region. Autoradiography analysis showed an absence of binding in homozygous mutant mice. (J:75722)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Htr1a Mutation:  14 strains or lines available
Original:  J:75722 Gross C, et al., Serotonin1A receptor acts during development to establish normal anxiety-like behaviour in the adult. Nature. 2002 Mar 28;416(6879):396-400
All:  5 reference(s)

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.11
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