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Tg(Rag2-Igb)1Mnz
Transgene Detail
Nomenclature
Symbol: Tg(Rag2-Igb)1Mnz
Name: transgene insertion 1, Michel C Nussenzweig
MGI ID: MGI:2387028
Synonyms: Igbetatg
Transgene: Tg(Rag2-Igb)1Mnz  Location: unknown  
Transgene
origin
Strain of Origin:  Not Applicable
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Mutation detailsThe Igb cDNA sequence was inserted into the Rag2 locus and used as the transgene. RT-PCR analysis showed that transgene expression pattern followed that of endogenous Rag2 in early developing B-cells.. (J:78601)
Phenotypes
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Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:78601 Meffre E, et al., Deletion of immunoglobulin beta in developing B cells leads to cell death. Proc Natl Acad Sci U S A. 2002 Aug 20;99(17):11334-9
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory