Tg(Rag2-Igb)1Mnz
Transgene Detail

Summary

• Symbol: Tg(Rag2-Igb)1Mnz
• Name: transgene insertion 1, Michel C Nussenzweig
• MGI ID: MGI:2387028
• Synonyms: Igbetatg
• Transgene: Tg(Rag2-Igb)1Mnz Location: unknown
• Alliance: Tg(Rag2-Igb)1Mnz page

Transgene origin

• Strain of Origin: Not Applicable

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Rag2-Igb)1Mnz expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Cd79b (MGI:96431)

• Mutation details: The Igb cDNA sequence was inserted into the Rag2 locus and used as the transgene. RT-PCR analysis showed that transgene expression pattern followed that of endogenous Rag2 in early developing B-cells.. (J:78601)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:78601 Meffre E, et al., Deletion of immunoglobulin beta in developing B cells leads to cell death. Proc Natl Acad Sci U S A. 2002 Aug 20;99(17):11334-9
• All: 1 reference(s)