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Targeted Allele Detail
Symbol: Cd79btm1Mnz
Name: CD79B antigen; targeted mutation 1, Michel C Nussenzweig
MGI ID: MGI:2387024
Synonyms: Igbeta-
Gene: Cd79b  Location: Chr11:106311341-106314562 bp, - strand  Genetic Position: Chr11, 68.89 cM
Germline Transmission:  Earliest citation of germline transmission: J:79045
Parent Cell Line:  CJ7 (ES Cell)
Strain of Origin:  129S1/Sv-Oca2+ Tyr+ Kitl+
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsThe gene was disrupted by replacement of the promoter, exon 1, and part of exon 2 with a neomycin resistance cassette. Northern blot of bone marrow RNA from homozygous mutant animals confirmed the absence of gene expression. (J:79045)
View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cd79b Mutation:  20 strains or lines available
Original:  J:79045 Gong S, et al., Regulation of an early developmental checkpoint in the B cell pathway by Ig beta. Science. 1996 Apr 19;272(5260):411-4
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory