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Targeted Allele Detail
Symbol: Oprd1tm1Kff
Name: opioid receptor, delta 1; targeted mutation 1, Brigitte L Kieffer
MGI ID: MGI:2387013
Synonyms: DOR-, Oprd1-
Gene: Oprd1  Location: Chr4:132110726-132144486 bp, - strand  Genetic Position: Chr4, 64.78 cM, cytoband D1-D3
Germline Transmission:  Earliest citation of germline transmission: J:62551
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129/Sv
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsExon 1, which encodes the translational start codon, was replaced by a neomycin selection cassette inserted by homologous recombination. A radiolabeled binding assay demonstrated complete functional ablation in homozygous mutant mice. (J:62551)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Oprd1 Mutation:  20 strains or lines available
Original:  J:62551 Filliol D, et al., Mice deficient for delta- and mu-opioid receptors exhibit opposing alterations of emotional responses. Nat Genet. 2000 Jun;25(2):195-200
All:  21 reference(s)

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.11
The Jackson Laboratory