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Mafgtm1Jeng
Targeted Allele Detail
Nomenclature
Symbol: Mafgtm1Jeng
Name: v-maf musculoaponeurotic fibrosarcoma oncogene family, protein G (avian); targeted mutation 1, James Douglas Engel
MGI ID: MGI:2386717
Synonyms: mafG-
Gene: Mafg  Location: Chr11:120625117-120633600 bp, - strand  Genetic Position: Chr11, 84.35 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:78982
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe entire coding region was replaced by a cassette containing lacZ and floxed tk-neo genes. The lacZ gene was situated immediately downstream of the translational start codon. RNAse protection assays were utilized to confirm the absence of transcript in homozygous mutant mice. Expression of beta-galactosidase was driven by the endogenous promoter. (J:78982)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 47 assay results
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Mafg Mutation:  28 strains or lines available
References
Original:  J:78982 Shavit JA, et al., Impaired megakaryopoiesis and behavioral defects in mafG-null mutant mice. Genes Dev. 1998 Jul 15;12(14):2164-74
All:  13 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/11/2020
MGI 6.14
The Jackson Laboratory