About   Help   FAQ
Ppardtm1Rev
Targeted Allele Detail
Nomenclature
Symbol: Ppardtm1Rev
Name: peroxisome proliferator activator receptor delta; targeted mutation 1, Ronald M Evans
MGI ID: MGI:2386683
Synonyms: Ppardeltack
Gene: Ppard  Location: Chr17:28232754-28301469 bp, + strand  Genetic Position: Chr17, 14.64 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:73557
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsExon 4, which encodes the amino terminal portion of the DNA binding domain was left flanked by single loxP sites after a downstream neo cassette was excised via the expression of cre recombinase in vitro. (J:73557)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Ppard Mutation:  60 strains or lines available
References
Original:  J:73557 Barak Y, et al., Effects of peroxisome proliferator-activated receptor delta on placentation, adiposity, and colorectal cancer. Proc Natl Acad Sci U S A. 2002 Jan 8;99(1):303-8
All:  34 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
04/06/2021
MGI 6.16
The Jackson Laboratory