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Targeted Allele Detail
Symbol: Ppardtm1Rev
Name: peroxisome proliferator activator receptor delta; targeted mutation 1, Ronald M Evans
MGI ID: MGI:2386683
Synonyms: Ppardeltack
Gene: Ppard  Location: Chr17:28232754-28301469 bp, + strand  Genetic Position: Chr17, 14.64 cM
Germline Transmission:  Earliest citation of germline transmission: J:73557
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
Mutation detailsExon 4, which encodes the amino terminal portion of the DNA binding domain was left flanked by single loxP sites after a downstream neo cassette was excised via the expression of cre recombinase in vitro. (J:73557)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Ppard Mutation:  60 strains or lines available
Original:  J:73557 Barak Y, et al., Effects of peroxisome proliferator-activated receptor delta on placentation, adiposity, and colorectal cancer. Proc Natl Acad Sci U S A. 2002 Jan 8;99(1):303-8
All:  34 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.16
The Jackson Laboratory