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Rargtm3.1Ipc
Targeted Allele Detail
Nomenclature
Symbol: Rargtm3.1Ipc
Name: retinoic acid receptor, gamma; targeted mutation 3.1, Pierre Chambon
MGI ID: MGI:2386112
Synonyms: RARgammaL-
Gene: Rarg  Location: Chr15:102234938-102257517 bp, - strand  Genetic Position: Chr15, 57.4 cM, cytoband E-F3
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:75133
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsThe floxed fragment containing exon 8 was excised from Rargtm3Ipc by the ubiquitous in vivo expression of cre recombinase. The deletion eliminated the majority of the DNA binding domain and introduced a frameshift mutation. A lack of protein expression was demonstrated in homozygous mutant mice via immunohistochemical analysis of skin sections. (J:75133)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rarg Mutation:  156 strains or lines available
References
Original:  J:75133 Chapellier B, et al., A conditional floxed (loxP-flanked) allele for the retinoic acid receptor gamma (RARgamma) gene. Genesis. 2002 Feb;32(2):95-8
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
06/13/2017
MGI 6.10
The Jackson Laboratory