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Mafktm1Sho
Targeted Allele Detail
Nomenclature
Symbol: Mafktm1Sho
Name: v-maf musculoaponeurotic fibrosarcoma oncogene family, protein K (avian); targeted mutation 1, Stuart Orkin
MGI ID: MGI:2385844
Synonyms: p18 NF-E2 -
Gene: Mafk  Location: Chr5:139791536-139802653 bp, + strand  Genetic Position: Chr5, 78.81 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:35116
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe third exon, encoding most of the protein including the basic zipper domain, was replaced by a neomycin selection cassette. (J:35116)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 2 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Mafk Mutation:  5 strains or lines available
References
Original:  J:35116 Kotkow KJ, et al., Complexity of the erythroid transcription factor NF-E2 as revealed by gene targeting of the mouse p18 NF-E2 locus. Proc Natl Acad Sci U S A. 1996 Apr 16;93(8):3514-8
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/16/2021
MGI 6.16
The Jackson Laboratory