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Tsg101tm1Mak
Targeted Allele Detail
Nomenclature
Symbol: Tsg101tm1Mak
Name: tumor susceptibility gene 101; targeted mutation 1, Tak W Mak
MGI ID: MGI:2385839
Synonyms: tsg101-
Gene: Tsg101  Location: Chr7:46888949-46919969 bp, - strand  Genetic Position: Chr7, 30.62 cM, cytoband B5
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:67553
Parent Cell Line:  E14K (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsAll of exon 8 and a 5' portion of exon 9 were replaced with a neomycin selection cassette. Transcript was undetected by in situ hybridization of homozygous mutant embryos. (J:67553)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tsg101 Mutation:  17 strains or lines available
References
Original:  J:67553 Ruland J, et al., p53 accumulation, defective cell proliferation, and early embryonic lethality in mice lacking tsg101. Proc Natl Acad Sci U S A. 2001 Feb 13;98(4):1859-64
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory