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Hsd17b4tm1Baes
Targeted Allele Detail
Nomenclature
Symbol: Hsd17b4tm1Baes
Name: hydroxysteroid (17-beta) dehydrogenase 4; targeted mutation 1, Myriam Baes
MGI ID: MGI:2385822
Synonyms: D-PBE-, MFP-2-, MFP2-
Gene: Hsd17b4  Location: Chr18:50128201-50196269 bp, + strand  Genetic Position: Chr18, 27.24 cM
Growth retardation and hypotonia in Ehhadhtm1Jkr/Ehhadhtm1Jkr Hsd17b4tm1Baes/Hsd17b4tm1Baes mice

Show the 3 phenotype image(s) involving this allele.

Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:62314
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hsd17b4 Mutation:  6 strains or lines available
References
Original:  J:62314 Baes M, et al., Inactivation of the peroxisomal multifunctional protein-2 in mice impedes the degradation of not only 2-methyl-branched fatty acids and bile acid intermediates but also of very long chain fatty acids. J Biol Chem. 2000 May 26;275(21):16329-36
All:  11 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/16/2014
MGI 5.20
The Jackson Laboratory