Tg(Cyp19)C2-3Rrte
Transgene Detail
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Symbol: |
Tg(Cyp19)C2-3Rrte |
Name: |
transgene insertion C2-3, Rajeshwar Rao Tekmal |
MGI ID: |
MGI:2385806 |
Synonyms: |
int-5-aromatase, MMTV-int-5-aromatase transgene |
Transgene: |
Tg(Cyp19)C2-3Rrte Location: unknown
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Alliance: |
Tg(Cyp19)C2-3Rrte page
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Transgene Type: |
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Transgenic (Inserted expressed sequence) |
Mutation: |
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Insertion
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Tg(Cyp19)C2-3Rrte expresses
1 gene
Transgene expresses:
Organism |
Expressed Gene |
Note |
mouse |
Cyp19a1 (MGI:88587) |
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Mutation details: This transgene was produced using a vector that contained the 2.4kb full-length mouse Cyp 19 cDNA in addition to a coding region that included -45 to -1 of 5' and a complete (860bp) 3' untranslated region under the control of a mouse mammary tumor virus promoter (MMTV). Multiple lines were generated, ranging in copy number from 1 to 30, estimated by Southern blot. This allele is representative of the high copy number variants and carries an estimated 20 copies of the gene in mammary gland tissue.
(J:34063)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Original: |
J:34063 Tekmal RR, et al., Overexpression of int-5/aromatase in mammary glands of transgenic mice results in the induction of hyperplasia and nuclear abnormalities. Cancer Res. 1996 Jul 15;56(14):3180-5 |
All: |
12 reference(s) |
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