Lhx1^tm2Bhr
Targeted Allele Detail

Summary

• Symbol: Lhx1^tm2Bhr
• Name: LIM homeobox protein 1; targeted mutation 2, Richard R Behringer
• MGI ID: MGI:2385715
• Synonyms: Lim1-floxed-neo
• Gene: Lhx1 Location: Chr11:84409110-84416361 bp, - strand Genetic Position: Chr11, 51.31 cM
• Alliance: Lhx1^tm2Bhr page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:75126
• Parent Cell Line: AB1 (ES Cell)
• Strain of Origin: 129S7/SvEvBrd-Hprt1⁺

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: The entire coding region of the endogenous locus was flanked by a loxP site inserted into the untranslated region of exon 1 and a floxed neo cassette insertered downstream of the stop codon. (J:75126)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Lhx1 Mutation: 21 strains or lines available

References

• Original: J:75126 Kwan KM, et al., Conditional inactivation of Lim1 function. Genesis. 2002 Feb;32(2):118-20
• All: 2 reference(s)