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Rbl1tm1Htr
Targeted Allele Detail
Nomenclature
Symbol: Rbl1tm1Htr
Name: retinoblastoma-like 1 (p107); targeted mutation 1, Hein te Riele
MGI ID: MGI:2385659
Synonyms: p107-
Gene: Rbl1  Location: Chr2:157145893-157204534 bp, - strand  Genetic Position: Chr2, 78.05 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:48194
Parent Cell Line:  IB10/E14IB10 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Insertion
 
Mutation detailsRbl1 was disrupted by insertion of a promoterless IRES Beta-geo cassette behind codon 145 via homologous recombination resulting in an in-frame termination codon originating within the IRES sequence. (J:48194)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rbl1 Mutation:  11 strains or lines available
References
Original:  J:48194 Robanus-Maandag E, et al., p107 is a suppressor of retinoblastoma development in pRb-deficient mice. Genes Dev. 1998 Jun 1;12(11):1599-609
All:  8 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
05/12/2015
MGI 5.21
The Jackson Laboratory