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Srftm2Nor
Targeted Allele Detail
Nomenclature
Symbol: Srftm2Nor
Name: serum response factor; targeted mutation 2, Alfred Nordheim
MGI ID: MGI:2385464
Synonyms: fl, Srff, Srf-flex1neo
Gene: Srf  Location: Chr17:46548329-46556175 bp, - strand  Genetic Position: Chr17, 22.9 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:75123
Parent Cell Line:  E14.1 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA construct, in which the coding region of exon 1 was flanked by a single loxP site in the 5' untranslated region and a floxed neo cassette in intron 1, was incorporated at the endogenous locus via homologous recombination. (J:75123)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Srf Mutation:  3 strains or lines available
References
Original:  J:75123 Wiebel FF, et al., Generation of mice carrying conditional knockout alleles for the transcription factor SRF. Genesis. 2002 Feb;32(2):124-6
All:  9 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/18/2020
MGI 6.14
The Jackson Laboratory