Rps6ka4^tm1.2Gsc
Targeted Allele Detail

Summary

• Symbol: Rps6ka4^tm1.2Gsc
• Name: ribosomal protein S6 kinase, polypeptide 4; targeted mutation 1.2, Gunther Schutz
• MGI ID: MGI:2384591
• Gene: Rps6ka4 Location: Chr19:6806578-6818004 bp, - strand Genetic Position: Chr19, 5.08 cM
• Alliance: Rps6ka4^tm1.2Gsc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:75113
• Parent Cell Line: E14.1 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: A fragment containing 2 exons encoding the ATP-binding domain was excised, leaving a single loxP site. Truncated transcript was detected by RT-PCR analysis of total renal RNA isolated from heterozygous mice. This allele was generated by the breeding of mice carrying Rps6ka4^tm1.1Gsc with transgenic mice expressing cre recombinase via a ubiquitous promoter. (J:75113)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rps6ka4 Mutation: 35 strains or lines available

Notes

No phenotypic information associated with this allele was reported.

References

• Original: J:75113 Casanova E, et al., Construction of a conditional allele of RSK-B/MSK2 in the mouse. Genesis. 2002 Feb;32(2):158-60
• All: 1 reference(s)