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Pitx2tm1Rsd
Targeted Allele Detail
Nomenclature
Symbol: Pitx2tm1Rsd
Name: paired-like homeodomain transcription factor 2; targeted mutation 1, Michael G Rosenfeld
MGI ID: MGI:2384494
Synonyms: Pitx2-, Pitx2LacZ
Gene: Pitx2  Location: Chr3:129199878-129219591 bp, + strand  Genetic Position: Chr3, 57.84 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:57673
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Expression
In Mice Carrying this Mutation: 266 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pitx2 Mutation:  13 strains or lines available
References
Original:  J:57673 Lin CR, et al., Pitx2 regulates lung asymmetry, cardiac positioning and pituitary and tooth morphogenesis. Nature. 1999 Sep 16;401(6750):279-82
All:  8 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/12/2014
MGI 5.19
The Jackson Laboratory