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Egr1tm1Jmi
Targeted Allele Detail
Nomenclature
Symbol: Egr1tm1Jmi
Name: early growth response 1; targeted mutation 1, Jeffrey Milbrandt
MGI ID: MGI:2384433
Synonyms: egr-1-, Egr1-, Egr-10, Egr-1ko, NGFI-A-
Gene: Egr1  Location: Chr18:34859823-34864984 bp, + strand  Genetic Position: Chr18, 18.76 cM, cytoband C/D
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:24948
Parent Cell Line:  Other (see notes) (ES Cell)
Strain of Origin:  129
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Egr1 Mutation:  7 strains or lines available
Notes
ES cell line = AB1 (129S7/SvEvBrd-Hprt+) or D3 (129S2/SvPas). Phenotypic Similarity to Human Syndrome: Myeloproliferative disorder J:123870 background involves: 129 * C57BL/6

References
Original:  J:24948 Lee SL, et al., Growth and differentiation proceeds normally in cells deficient in the immediate early gene NGFI-A. J Biol Chem. 1995 Apr 28;270(17):9971-7
All:  64 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/16/2014
MGI 5.19
The Jackson Laboratory